We thank Dr. Thomas Reji for helpful discussions and Perur Nishad for assistance with the graphics. This work was supported by a grant-in-aid for science research in the priority area “New Frontiers in Photochromism (No. 471)” from the Ministry of Education, Culture, Sports, Science, and Technology (MEXT) (Japan).
Induction of Point Chirality by E/Z Photoisomerization†
Article first published online: 4 NOV 2011
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 50, Issue 49, pages 11729–11730, December 2, 2011
How to Cite
Hashim, P. K. and Tamaoki, N. (2011), Induction of Point Chirality by E/Z Photoisomerization. Angew. Chem. Int. Ed., 50: 11729–11730. doi: 10.1002/anie.201104614
- Issue published online: 28 NOV 2011
- Article first published online: 4 NOV 2011
- Manuscript Received: 5 JUL 2011
- Ministry of Education, Culture, Sports, Science, and Technology (MEXT) (Japan)
- azo compounds;
- circular dichroism;
Shining a light on it: E/Z photoisomerization generates an asymmetric center and the corresponding separable enantiomers in an azobenzene-based prochiral molecule. This asymmetric center is formed by light-induced changes to the substituents on the central atom, and Z/E thermal isomerization regenerates the initial symmetry in the molecule. This switching of the asymmetry can be performed repeatedly.