Formation of Enantiomeric Impeller-Like Helical Architectures by DNA Self-Assembly and Silica Mineralization


  • We acknowledge the support of the National Natural Science Foundation of China (Grant No. 20821140537), the 973 project (2009CB930403), and Grand New Drug Development Program (No. 2009ZX09310-007) of China.


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Impeller-like helical DNA–silica complexes (see picture; green: silica) were synthesized in the presence of magnesium ions (a). DNA chiral packing and corresponding macroscopic helical morphologies are tuned by the change of reaction temperature, pH value, and molar ratio (b) of the quaternary ammonium (yellow)/phosphate group.