We thank the National Science Council, Taiwan for financial support of this work.
Gold-Catalyzed Intermolecular [4+2] and [2+2+2] Cycloadditions of Ynamides with Alkenes†
Article first published online: 11 NOV 2011
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 51, Issue 1, pages 113–117, January 2, 2012
How to Cite
Dateer, R. B., Shaibu, B. S. and Liu, R.-S. (2012), Gold-Catalyzed Intermolecular [4+2] and [2+2+2] Cycloadditions of Ynamides with Alkenes. Angew. Chem. Int. Ed., 51: 113–117. doi: 10.1002/anie.201105921
- Issue published online: 29 DEC 2011
- Article first published online: 11 NOV 2011
- Manuscript Revised: 13 OCT 2011
- Manuscript Received: 22 AUG 2011
- National Science Council, Taiwan
As good as gold: Gold-catalyzed intermolecular [4+2] cycloadditions of 2-arylynamides with alkenes and gold-catalyzed [2+2+2] cycloadditions of terminal ynamides with enol ethers have been developed (see scheme). The [4+2] cycloaddition is compatible with a range of alkenes and arylynamides and the [2+2+2] cycloaddition can also accommodate a variety of different arylynamide and enol ether substrates.