We whould like to thank the EPSRC (Grant No. EP/E059376/1 to N.F.), COST Network CM0802, and Rhodia for support and Johnson–Matthey for the loan of precious metals.
1521-3773/asset/2002_left.gif?v=1&s=ac6b0d94a94d7ce7a210002b8096b42feffc0bcf)
1521-3773/asset/olbannercenter.gif?v=1&s=c083e1920cd41ed129901c116018eab93b5ad3c4)
1521-3773/asset/2002_right.gif?v=1&s=451042aa3415ae3ad0729984d26dee1866aca82e)
Communication
Stable Fluorophosphines: Predicted and Realized Ligands for Catalysis†
Article first published online: 11 NOV 2011
DOI: 10.1002/anie.201105954
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Fey, N., Garland, M., Hopewell, J. P., McMullin, C. L., Mastroianni, S., Orpen, A. G. and Pringle, P. G. (2012), Stable Fluorophosphines: Predicted and Realized Ligands for Catalysis. Angew. Chem. Int. Ed., 51: 118–122. doi: 10.1002/anie.201105954
- †
Publication History
- Issue published online: 29 DEC 2011
- Article first published online: 11 NOV 2011
- Manuscript Received: 23 AUG 2011
Funded by
- EPSRC. Grant Number: EP/E059376/1
- COST Network
Keywords:
- homogeneous catalysis;
- hydrocyanation;
- hydroformylation;
- phosphacycles;
- phosphane ligands
Ligand maps lead to treasure! The activity of complexes of fluorophosphines (R2PF) in catalytic hydroformylation and hydrocyanation is predicted from a ligand map. However, the instability of R2PF to disproportionation is well-documented. Examples of R2PF ligands (see scheme) are described that are stabilized to such an extent that they can be used in catalysis and are shown to be highly effective.