We whould like to thank the EPSRC (Grant No. EP/E059376/1 to N.F.), COST Network CM0802, and Rhodia for support and Johnson–Matthey for the loan of precious metals.
Stable Fluorophosphines: Predicted and Realized Ligands for Catalysis†
Article first published online: 11 NOV 2011
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 51, Issue 1, pages 118–122, January 2, 2012
How to Cite
Fey, N., Garland, M., Hopewell, J. P., McMullin, C. L., Mastroianni, S., Orpen, A. G. and Pringle, P. G. (2012), Stable Fluorophosphines: Predicted and Realized Ligands for Catalysis. Angew. Chem. Int. Ed., 51: 118–122. doi: 10.1002/anie.201105954
- Issue published online: 29 DEC 2011
- Article first published online: 11 NOV 2011
- Manuscript Received: 23 AUG 2011
- EPSRC. Grant Number: EP/E059376/1
- COST Network
- homogeneous catalysis;
- phosphane ligands
Ligand maps lead to treasure! The activity of complexes of fluorophosphines (R2PF) in catalytic hydroformylation and hydrocyanation is predicted from a ligand map. However, the instability of R2PF to disproportionation is well-documented. Examples of R2PF ligands (see scheme) are described that are stabilized to such an extent that they can be used in catalysis and are shown to be highly effective.