Three-Component [2+2+2] Cycloaddition of Carboryne, Unactivated Alkene, and Alkyne via Zirconacyclopentane Mediated by Nickel: One-Pot Synthesis of Dihydrobenzocarboranes

Authors

  • Dr. Shikuo Ren,

    1. Department of Chemistry and State Key Laboratory on Synthetic Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong (China)
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  • Dr. Zaozao Qiu,

    1. Department of Chemistry and State Key Laboratory on Synthetic Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong (China)
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  • Prof. Dr. Zuowei Xie

    Corresponding author
    1. Department of Chemistry and State Key Laboratory on Synthetic Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong (China)
    • Department of Chemistry and State Key Laboratory on Synthetic Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong (China)
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  • The work described in this paper was supported by grants from the Research Grants Council of the Hong Kong Special Administration Region (Project No. 404011) and The Chinese University of Hong Kong.

Abstract

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Mix three—get one: The complexation of a transition-metal center to an olefin or alkyne can significantly modify its reactivity, which makes the selective coupling of different alkenes or alkynes to carboryne possible. An example of a three-component [2+2+2] cycloaddition reaction of carboryne with unactivated alkene (see scheme, blue) and alkyne (red) mediated by zirconium and nickel complexes is described.

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