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Keywords:

  • angiogenesis;
  • antibody–drug conjugates;
  • cancer;
  • cemadotin;
  • drug delivery
Thumbnail image of graphical abstract

Right on target: A chemically defined vascular-targeting antibody–drug conjugate (ADC) that offers comprehensive tumor coverage has been developed. When injected intravenously, this ADC potently inhibited tumor growth in a syngeneic immunocompetent model of murine cancer which cannot be cured by conventional cytotoxic agents.