We thank all members of our research group for their contributions and the DFG and BMBF for financial support.
Plug and Play with RNA†
Article first published online: 15 NOV 2011
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 50, Issue 52, pages 12400–12401, December 23, 2011
How to Cite
Mayer, G., Lennarz, S., Rohrbach, F. and Tolle, F. (2011), Plug and Play with RNA. Angew. Chem. Int. Ed., 50: 12400–12401. doi: 10.1002/anie.201106636
- Issue published online: 21 DEC 2011
- Article first published online: 15 NOV 2011
- Manuscript Received: 19 SEP 2011
- supramolecular chemistry
Retooling RNA: RNA aptamers are high-affinity ligands that can be assembled with other structures to yield multivalent molecules. These properties have been addressed in two recent studies: One describes a GFP-like RNA reporter used to study the dynamics of endogenous RNA; the other study reports on an aptamer-templated assembly of multi-enzyme complexes in bacteria for the controlled production of secondary molecules (see picture).