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Decoding Genomes at High Speed: Implications for Science and Medicine

Authors

  • Prof. Shankar Balasubramanian

    Corresponding author
    1. Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW (UK)
    2. Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE (UK)
    3. School of Clinical Medicine, University of Cambridge, Cambridge, CB2 0SP (UK)
    • Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW (UK)
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Abstract

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At warp speed: The speed and cost of sequencing DNA has undergone tremendous improvement based on Solexa sequencing. This technique arose from basic curiosity-driven research and unexpected outcomes, rather than from ideas that were strategically driven. The whole-genome sequencing of individuals now possible may one day transform the way medical disorders are classified, diagnosed, and treated.

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