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Controlled Origami Folding of Hydrogel Bilayers with Sustained Reversibility for Robust Microcarriers


  • This work was supported by a grant from the Creative Research Initiative Program of the Ministry of Education, Science, and Technology for “Complementary Hybridization of Optical and Fluidic Devices for Integrated Optofluidic Systems.”


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Soft origami structures: Planar bilayer microparticles consisting of active and passive layers show a structural transformation to microcapsules because of an anisotropic volume expansion (see picture). The soft hydrogel materials used for both layers facilitate the reversible transformation and complete closure of the compartment, which enables in situ encapsulation and triggered release of micro- to nanoscopic active ingredients.