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Keywords:

  • ABPP;
  • fluorescence imaging;
  • fluorescent probes;
  • KIAA1363;
  • serine hydrolases
Thumbnail image of graphical abstract

Profiling enzyme activities: A selective, activity-based imaging probe is described for the integral membrane hydrolase KIAA1363 and used to determine the subcellular localization and half-life of this enzyme in human cancer cells (see picture).