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Keywords:

  • DNA;
  • lasers;
  • molecular beacons;
  • optofluidics;
  • sensors
Thumbnail image of graphical abstract

Laser precision: A highly sensitive technique based on laser emission for differentiating a target DNA strand from strands that contain single base mismatches has been developed. Laser emission is used to amplify the small difference in signals that are generated by the different strands after hybridization with a molecular beacon (MB, see picture) in a conversion that is similar to analog-to-digital.