M.O. is indebted to the Einstein Foundation (Berlin) for an endowed professorship.
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A New Direction in C![[BOND]](http://onlinelibrarystatic.wiley.com/undisplayable_characters/00f8ff.gif)
H Alkenylation: Silanol as a Helping Hand†
Article first published online: 16 JAN 2012
DOI: 10.1002/anie.201107859
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Mewald, M., Schiffner, J. A. and Oestreich, M. (2012), A New Direction in CH Alkenylation: Silanol as a Helping Hand. Angew. Chem. Int. Ed., 51: 1763–1765. doi: 10.1002/anie.201107859
- †
Publication History
- Issue published online: 14 FEB 2012
- Article first published online: 16 JAN 2012
- Manuscript Received: 8 NOV 2011
- Abstract
- Article
- References
- Cited By
Keywords:
- alkenylation;
- CH activation;
- cross-coupling;
- directing groups;
- silicon
Director's cut: Not only conventional alcohols but also silanols can act as directing groups in oxidative palladium(II)-catalyzed CH alkenylations. The silicon-tethered hydroxy groups are “traceless”, thereby facilitating the regioselective CH activation of toluene derivitives as well as phenols (see scheme).