Financial support from the Spanish Ministry of Science and Innovation (MICINN, 2010/CSD2007-00013, CTQ2009-14363, CTQ2011-22923), and the Basque Government (Consolidated Groups) is gratefully acknowledged. J.U.G. thanks additionally the Deutsche Forschungsgemeinschaft and the Land Niedersachsen. E.J.C. acknowledges also a “Ramón y Cajal” contract from the MICINN. Computational resources and laser facilities of the UPV-EHU were used in this work (SGIker and I2Basque).
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Communication
Ribose Found in the Gas Phase†
Article first published online: 28 DEC 2011
DOI: 10.1002/anie.201107973
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Cocinero, E. J., Lesarri, A., Écija, P., Basterretxea, F. J., Grabow, J.-U., Fernández, J. A. and Castaño, F. (2012), Ribose Found in the Gas Phase. Angew. Chem. Int. Ed., 51: 3119–3124. doi: 10.1002/anie.201107973
- †
Publication History
- Issue published online: 21 MAR 2012
- Article first published online: 28 DEC 2011
- Manuscript Received: 12 NOV 2011
Funded by
- Spanish Ministry of Science and Innovation. Grant Numbers: 2010/CSD2007-00013, CTQ2009-14363, CTQ2011-22923
- Basque Government
- Deutsche Forschungsgemeinschaft
- Land Niedersachsen
Keywords:
- conformational analysis;
- hydrogen bonding;
- ribose;
- rotational spectroscopy;
- sugars
Sweet truth: The search for sugars in interstellar space is hampered by a lack of spectroscopic information. D-Ribose is now the first C5 sugar observed in the gas phase using microwave spectroscopy. The rotational spectrum revealed six conformations of free ribose, adopting preferentially β-pyranose rings and higher-energy α-pyranose forms. No evidence of α-/β-furanoses or linear forms was found, unlike biological systems, where β-furanoses are found in RNA.