We thank the National Science Council, Taiwan, for financial support of this work.
Gold-Catalyzed Oxidative Cyclizations of cis-3-En-1-ynes To Form Cyclopentenone Derivatives†
Article first published online: 1 FEB 2012
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 51, Issue 12, pages 2939–2942, March 19, 2012
How to Cite
Bhunia, S., Ghorpade, S., Huple, D. B. and Liu, R.-S. (2012), Gold-Catalyzed Oxidative Cyclizations of cis-3-En-1-ynes To Form Cyclopentenone Derivatives . Angew. Chem. Int. Ed., 51: 2939–2942. doi: 10.1002/anie.201108027
- Issue published online: 13 MAR 2012
- Article first published online: 1 FEB 2012
- Manuscript Revised: 21 DEC 2011
- Manuscript Received: 15 NOV 2011
- National Science Council, Taiwan
- CH insertion;
- synthetic methods
Golden tendencies: The title reaction for synthesizing cyclopentenone derivatives utilizes a gold complex and 8-methylquinoline oxide as the catalyst system (see scheme; IPr=1,3-bis(diisopropylphenyl)imidazol-2-ylidene). Such products are not attainable using diazocarbonyl reagents, as the gold carbenoids tend to react with CH bonds.