Flip a switch: A nanoswitch uses chemical inputs to turn an organocatalytic Knoevenagel reaction on and off (see scheme: R=reactant, P=product). To stop catalysis the chemical input (pink and green) wraps around the inhibitory segment of the nanoswitch to effect release or unlocking of the switch. The process can run reversibly over three cycles without loss of activity.
If you can't find a tool you're looking for, please click the link at the top of the page to "Go to old article view". Alternatively, view our Knowledge Base articles for additional help. Your feedback is important to us, so please let us know if you have comments or ideas for improvement.