Back Cover

Back Cover: Photoreversible Patterning of Biomolecules within Click-Based Hydrogels (Angew. Chem. Int. Ed. 8/2012)

  1. Dr. Cole A. DeForest,
  2. Prof. Kristi S. Anseth*

Article first published online: 8 DEC 2011

DOI: 10.1002/anie.201108165

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 51, Issue 8, page 1978, February 20, 2012

Additional Information

How to Cite

DeForest, C. A. and Anseth, K. S. (2012), Back Cover: Photoreversible Patterning of Biomolecules within Click-Based Hydrogels (Angew. Chem. Int. Ed. 8/2012). Angew. Chem. Int. Ed., 51: 1978. doi: 10.1002/anie.201108165

Author Information

  1. Chemical & Biological Engineering, University of Colorado and the Howard Hughes Medical Institute, 424 UCB, Boulder, CO 80309-0424 (USA) http://www.colorado.edu/che/ansethgroup/

*Chemical & Biological Engineering, University of Colorado and the Howard Hughes Medical Institute, 424 UCB, Boulder, CO 80309-0424 (USA) http://www.colorado.edu/che/ansethgroup/

Publication History

  1. Issue published online: 14 FEB 2012
  2. Article first published online: 8 DEC 2011

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Keywords:

  • bioorganic chemistry;
  • hydrogels;
  • peptides;
  • photochemistry;
  • RGD peptides
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Reversible biomolecular patterning in hydrogels can direct cell function in a user-defined manner. In their Communication on page 1816 ff., K. S. Anseth and C. A DeForest report 4D spatiotemporal control over the presentation of bioligands by using a thiol–ene photoconjugation reaction, which is initiated by visible light, combined with the photocleavage of an o-nitrobenzyl ether, which is controlled by UV light. This method allows cell functions to be probed dynamically.

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