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Keywords:

  • DNA recognition;
  • DNA structures;
  • proteins;
  • self-assembly;
  • zinc finger
Thumbnail image of graphical abstract

Point the finger: Zinc-finger proteins are convenient and site-selective adaptors for targeting specific locations within DNA-origami structures. Orthogonal targeting of the specific locations in the structures was demonstrated by using two adaptors, and the application of Escherichia coli lysate that contained the adaptor-fused proteins successfully afforded the expected protein–DNA assembly.