SEARCH

SEARCH BY CITATION

Keywords:

  • gels;
  • insulin;
  • phenylboronates;
  • polymers;
  • skin layer
Thumbnail image of graphical abstract

A totally synthetic artificial pancreas is described by Y. Miyahara et al. in their Communication on page 2124 ff. A hydrogel bearing a phenylboronate derivative undergoes a glucose-dependent transition in its state of hydration under physiological conditions. The reversible surface-localized dehydration enables the provision of insulin to be controlled, thus offering a new basis for the treatment of diabetes with long-term stability and safety.