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Copper-Catalyzed Amination of Arylboronates with N,N-Dialkylhydroxylamines


  • This work was partly supported by Grants-in-Aid from the Ministry of Education, Culture, Sports, Science, and Technology (Japan). K.H. acknowledges Kansai Research Foundation for the Promotion of Science.


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A tolerant coupling: The title reaction has been developed to deliver arylamines (see scheme; Bz=benzoyl, dppbz=1,2-bis(diphenylphosphino)benzene). The catalysis is based on electrophilic, umpolung amination and enables the use of secondary acyclic amines. Various functional groups are tolerated, thus opening up a new substrate class for the Chan–Lam-type coupling.

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