Highly Stable Silver Nanoplates for Surface Plasmon Resonance Biosensing


  • This work was supported by the National Science Foundation under Grant Nos. DMR-0956081 (Y.Y.) and CHE-1059050 (Q.C.). Y.Y. also thanks the Research Corporation for Science Advancement for the Cottrell Scholar Award and DuPont for the Young Professor grant. Part of the TEM work was performed at ORNL’s Shared Research Equipment (SHaRE) User Facility, which is sponsored by the Office of Basic Energy Sciences, U.S. DOE.


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An SPR biosensor was developed by employing highly stable Au-protected Ag nanoplates (NP) as enhancers (see picture). Superior performance was achieved by depositing a thin and uniform coating of Au on the Ag surface while minimizing disruptive galvanic replacement and retaining the strong surface plasmon resonance (SPR) of the silver nanoplates.