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Keywords:

  • bacterial toxin;
  • blood group;
  • calorimetry;
  • carbohydrates
Thumbnail image of graphical abstract

It has long been known that people with blood group O are more severely affected by El Tor cholera than those with blood groups A or B. Microcalorimetry and NMR spectroscopy are used to evaluate the ability of the B-subunits of cholera toxin and E. coli heat-labile toxin to bind to selected blood group oligosaccharides.