Back Cover: Enantioselective Alkynylbenzaldehyde Cyclizations Catalyzed by Chiral Gold(I) Acyclic Diaminocarbene Complexes Containing Weak Au–Arene Interactions (Angew. Chem. Int. Ed. 12/2012)



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Creating an asymmetric environment at AuI is a challenge because of the linear coordination geometry of the ion. In their Communication on page 2912 ff., S. Handa and L. M. Slaughter report the highly enantioselective catalysis of a tandem addition/cycloisomerization reaction of alkynylbenzaldehydes by chiral gold carbene complexes containing weak metal–π interactions. These secondary interactions help to create an asymmetric pocket around the gold atom that is analogous to a baseball glove gripping a ball. (Picture by L. M. Slaughter and S. Ball.)