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Communication

A Genetically Encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper-Free Click Reaction†

  1. Dipl.-Ing. Emine Kaya‡,
  2. Dr. Milan Vrabel‡,
  3. M. Sc. Christian Deiml,
  4. M. Sc. Stefan Prill,
  5. Dr. Viviana S. Fluxa,
  6. Prof. Dr. Thomas Carell*

Article first published online: 21 MAR 2012

DOI: 10.1002/anie.201109252

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 51, Issue 18, pages 4466–4469, April 27, 2012

Additional Information

How to Cite

Kaya, E., Vrabel, M., Deiml, C., Prill, S., Fluxa, V. S. and Carell, T. (2012), A Genetically Encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper-Free Click Reaction . Angew. Chem. Int. Ed., 51: 4466–4469. doi: 10.1002/anie.201109252

Author Information

  1. Department Chemie, Ludwig-Maximilians-Universität, Butenandtstrasse 5–13, 81377 Munich (Germany) http://www.carellgroup.de

  1. ‡

    These authors contributed equally to this work.

*Department Chemie, Ludwig-Maximilians-Universität, Butenandtstrasse 5–13, 81377 Munich (Germany) http://www.carellgroup.de

  1. †

    We thank Prof. Dr. Manfred T. Reetz and Dr. Despina Bougioukou for their assistance with the site-directed mutagenesis experiments. We thank Bayer Pharma AG, the Excellence Cluster CiPSM, and the Volkswagen Foundation for generous support. M.V. thanks the LMU Munich for a postdoctoral fellowship. V.S.F. thanks the SNSF for a postdoctoral fellowship.

  2. ‡

    These authors contributed equally to this work.

Publication History

  1. Issue published online: 24 APR 2012
  2. Article first published online: 21 MAR 2012
  3. Manuscript Received: 30 DEC 2011

Funded by

  • Excellence Cluster CiPSM
  • Volkswagen Foundation
Corrected by:

Corrigendum: Corrigendum: A Genetically Encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper-Free Click Reaction

Vol. 51, Issue 22, 5277, Article first published online: 23 MAY 2012

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View Full Article with Supporting Information (HTML) Get PDF (727K)