SEARCH

SEARCH BY CITATION

Keywords:

  • amines;
  • chemoselectivity;
  • imines;
  • oxidation;
  • homogeneous catalysis
Thumbnail image of graphical abstract

Acting together: Low catalytic amounts of CuI and topaquinone-like catalyst 1ox (see scheme) are sufficient to activate the α-C[BOND]H bond of primary amines, which are converted into alkylated imines under ambient conditions. This atom-economical process tolerates the presence of various reactive functional groups and allows selective cross-coupling of two amines.