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Towards a Green Process for Bulk-Scale Synthesis of Ethyl Acetate: Efficient Acceptorless Dehydrogenation of Ethanol


  • M.N. thanks the Alexander von Humboldt Foundation for financial support.


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Green is a go: An efficient acceptorless dehydrogenative dimerization of ethanol to give ethyl acetate was realized (see scheme). The reaction proceeds under mild reaction conditions in the presence of a ruthenium catalyst with concomitant liberation of molecular hydrogen, which can be used as a valuable product itself. At low catalyst loading (50 ppm), high yields of ethyl acetate and excellent catalyst turnover numbers are achieved.