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Keywords:

  • α-synuclein;
  • photobleaching;
  • proteins;
  • single-molecule studies
Thumbnail image of graphical abstract

Bleaching proteins: Single-molecule photobleaching approaches and sub-stoichiometric labeling with fluorophores give insight into the number of monomers that form a specific α-synuclein oligomer. The results show that this α-synuclein oligomer is present as a single, well-defined species consisting of 31 monomers.