Visible-Light Photoredox Catalysis in Flow


  • Financial support for this research from the NSF (grant number CHE-1056568), the NIH-NIGMS (grant number R01-GM096129), the Alfred P. Sloan Foundation, Amgen, and Boehringer Ingelheim is gratefully acknowledged. J.W.T. thanks The American Chemical Society, Division of Organic Chemistry and Amgen for a graduate fellowship. NMR (CHE-0619339) and MS (CHE-0443618) facilities at BU are supported by the NSF.


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Photoredox catalysis: A variety of organic transformations mediated by visible-light-active photoredox catalysts have been conducted in a photochemical flow reactor. The reactor design is very simple and can be easily implemented in any laboratory (see picture). In addition, this reactor afforded a marked increase in the reaction rate compared to those observed in typical batch (round bottom flask) reactors.