Tamed Arene and Heteroarene Trifluoromethylation

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Abstract

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A tri-ing transformation: The increasingly high demand for trifluoromethylated arenes and heteroarenes is a major challenge that has been addressed through the development of trifluoromethylation reactions. Several effective approaches for late-stage trifluoromethylation, as well as the use of practical and cheap trifluoromethylation reagents, are highlighted.

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