Work performed in the lab of the author in related areas is supported by the National Institutes of Health (GM086925 and GM084933) and the GSU Molecular Basis of Disease program.
Dual-Responsive Boronate Crosslinked Micelles for Targeted Drug Delivery†
Article first published online: 18 APR 2012
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 51, Issue 22, pages 5293–5295, May 29, 2012
How to Cite
Chen, W., Cheng, Y. and Wang, B. (2012), Dual-Responsive Boronate Crosslinked Micelles for Targeted Drug Delivery . Angew. Chem. Int. Ed., 51: 5293–5295. doi: 10.1002/anie.201201179
- Issue published online: 23 MAY 2012
- Article first published online: 18 APR 2012
- Manuscript Received: 13 FEB 2012
- National Institutes of Health. Grant Numbers: GM086925, GM084933
- GSU Molecular Basis of Disease program
- drug delivery;
Controlled trigger finger: A novel class of micelles for targeted drug delivery was developed. The strategy relies on boronic acid–diol interactions as a way of accessing crosslinked micelles having improved stability (see scheme) and quick payload release in response to low pH environments or diol addition.