Dual-Responsive Boronate Crosslinked Micelles for Targeted Drug Delivery

Authors


  • Work performed in the lab of the author in related areas is supported by the National Institutes of Health (GM086925 and GM084933) and the GSU Molecular Basis of Disease program.

Abstract

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Controlled trigger finger: A novel class of micelles for targeted drug delivery was developed. The strategy relies on boronic acid–diol interactions as a way of accessing crosslinked micelles having improved stability (see scheme) and quick payload release in response to low pH environments or diol addition.

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