A Rotaxane-Based Switchable Organocatalyst


  • We thank the EPSRC National Mass Spectrometry Centre (Swansea (UK)) for high resolution mass spectrometry. This research was funded by the EPSRC. V.B. and A.C. are Marie Curie Fellows (IEF) within the 7th European Framework Program. We also thank Fundacja na Rzecz Nauki Polskiej (FNP) for a postdoctoral fellowship to B.L.


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Switch it on! The activity of an organocatalytic group incorporated within a rotaxane architecture can be controlled by switching the position of the macrocycle. The system was used to mediate the progress of the Michael addition of an aliphatic thiol to trans-cinnamaldehyde.