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Double Cyclization/Aryl Migration Across an Alkyne Bond Enabled by Organoboryl and Diarylplatinum Groups


  • We gratefully acknowledge the Natural Sciences and Engineering Council of Canada for financial support. We thank Prof. Nicholas Mosey for his assistance in DFT computations.


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Synergy between metals: Diarylacetylenes 1, containing both a boryl (BMes2) group and a diarylplatinum group, undergo a transformation involving a double metallocyclization/aryl migration to give tetracycles 2 in high diastereoselectivity (see scheme). This remarkable transformation is enabled by the synergistic interplay of the boryl and the diarylplatinum group.