This research was supported under the Australian Research Council Discovery projects funding scheme (DP1094564) and Centre of Excellence for Functional Nanomaterials (CE0348243). A special thank goes to Dr. Edith Chow for the gift of interdigitated electrodes and to Ms. Delfine Cheng for assistance in cryo-TEM preparation.
The Biochemiresistor: An Ultrasensitive Biosensor for Small Organic Molecules†
Article first published online: 25 MAY 2012
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 51, Issue 26, pages 6456–6459, June 25, 2012
How to Cite
Lai, L. M. H., Goon, I. Y., Chuah, K., Lim, M., Braet, F., Amal, R. and Gooding, J. J. (2012), The Biochemiresistor: An Ultrasensitive Biosensor for Small Organic Molecules . Angew. Chem. Int. Ed., 51: 6456–6459. doi: 10.1002/anie.201202350
- Issue published online: 21 JUN 2012
- Article first published online: 25 MAY 2012
- Manuscript Received: 26 MAR 2012
- Australian Research Council Discovery. Grant Numbers: DP1094564, CE0348243
- interdigitated electrodes;
- magnetic nanoparticles
New sensation: A resistance-based biosensor uses gold-coated magnetic nanoparticles (Au@MNPs) functionalized with the antibiotic enrofloxin (see picture; purple), which bind to anti-enrofloxin as analyte (blue). The Au@MNPs can be magnetically assembled between electrodes, and the measured resistance R is a function of analyte concentration.