Financial support from the National Basic Research Program of China (973 Program) (Grant No. 2009CB825300) and the National Science Foundation of China (Nos. 20872003, 21172006) are greatly appreciated. We thank Yijin Su and Yuepeng Yan in our group for reproducing the results of polystyrene.
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Communication
FeCl2-Promoted Cleavage of the Unactivated C![[BOND]](http://onlinelibrarystatic.wiley.com/undisplayable_characters/00f8ff.gif)
C Bond of Alkylarenes and Polystyrene: Direct Synthesis of Arylamines†
Article first published online: 11 JUN 2012
DOI: 10.1002/anie.201202464
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Qin, C., Shen, T., Tang, C. and Jiao, N. (2012), FeCl2-Promoted Cleavage of the Unactivated CC Bond of Alkylarenes and Polystyrene: Direct Synthesis of Arylamines . Angew. Chem. Int. Ed., 51: 6971–6975. doi: 10.1002/anie.201202464
- †
Publication History
- Issue published online: 4 JUL 2012
- Article first published online: 11 JUN 2012
- Manuscript Received: 29 MAR 2012
Funded by
- National Basic Research Program of China. Grant Number: 2009CB825300
- National Science Foundation. Grant Numbers: 20872003, 21172006
Keywords:
- amines;
- arenes;
- CC activation;
- iron;
- rearrangements
Ironing it out: An efficient and convenient nitrogenation strategy involving CC bond cleavage for the straightforward synthesis of versatile arylamines is presented. Various alkyl azides and alkylarenes, including the common industrial by-product cumene, react using this protocol. Moreover, this method provides a potential strategy for the degradation of polystyrene.