SEARCH

SEARCH BY CITATION

Keywords:

  • aldol reaction;
  • molecular diversity;
  • multicomponent reactions;
  • nitrogen heterocycles;
  • synthetic methods
Thumbnail image of graphical abstract

Complexity from simplicity: Nitrogen-containing heterocycles have been assembled by means of unprecedented domino processes designed to take advantage of diversity assembly using strategically decorated Ugi products (see scheme). The aldol reaction is the second common denominator which enables sequences of up to five steps in one pot, thus producing unique molecular architectures in rapid fashion.