This work was supported by the European Research Council (ERC Advanced grant No. 267173). We thank H. Haschke, JPK Instruments, for carrying out HyperDrive AFM measurements.
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Communication
Design Strategy for DNA Rotaxanes with a Mechanically Reinforced PX100 Axle†
Article first published online: 31 MAY 2012
DOI: 10.1002/anie.201202816
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Ackermann, D., Jester, S.-S. and Famulok, M. (2012), Design Strategy for DNA Rotaxanes with a Mechanically Reinforced PX100 Axle. Angew. Chem. Int. Ed., 51: 6771–6775. doi: 10.1002/anie.201202816
- †
Publication History
- Issue published online: 27 JUN 2012
- Article first published online: 31 MAY 2012
- Manuscript Received: 12 APR 2012
Funded by
- European Research Council
Keywords:
- DNA nanorings;
- DNA nanotechnology;
- DNA rotaxanes;
- paranemic crossover;
- pseudorotaxanes
Non-deformable axles based on paranemic crossover DNAs can serve as components for mechanically stable DNA rotaxanes. The required design strategies provide generally applicable guidelines for the incorporation of mechanically interlocked DNA architectures or even DNA origami structures. DNA rotaxanes with mechanically reinforced axles can serve as precursors for complex molecular machines capable of force transmission.