This work was supported by the NEXT Program and partly by Grant-in-Aid number 22685018 from JSPS. We thank Mr. T. Abe of Oxford Instruments for helpful discussion and technical assistance on the DNP experiments.
1521-3773/asset/2002_left.gif?v=1&s=ac6b0d94a94d7ce7a210002b8096b42feffc0bcf)
1521-3773/asset/olbannercenter.gif?v=1&s=c083e1920cd41ed129901c116018eab93b5ad3c4)
1521-3773/asset/2002_right.gif?v=1&s=451042aa3415ae3ad0729984d26dee1866aca82e)
Communication
Design of a 13C Magnetic Resonance Probe Using a Deuterated Methoxy Group as a Long-Lived Hyperpolarization Unit†
Article first published online: 7 SEP 2012
DOI: 10.1002/anie.201202885
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Issue
1521-3773/asset/cover.gif?v=1&s=412bc65bdcb3f0e34a94f27c1c13e908726694d4 "Angewandte Chemie International Edition")
Angewandte Chemie International Edition
Volume 51, Issue 40, pages 10114–10117, October 1, 2012
Additional Information
How to Cite
Doura, T., Hata, R., Nonaka, H., Ichikawa, K. and Sando, S. (2012), Design of a 13C Magnetic Resonance Probe Using a Deuterated Methoxy Group as a Long-Lived Hyperpolarization Unit . Angew. Chem. Int. Ed., 51: 10114–10117. doi: 10.1002/anie.201202885
- †
Publication History
- Issue published online: 26 SEP 2012
- Article first published online: 7 SEP 2012
- Manuscript Revised: 26 JUN 2012
- Manuscript Received: 16 APR 2012
Funded by
- NEXT Program. Grant Number: 22685018
- JSPS
Keywords:
- deuteration;
- dipole–dipole interactions;
- hyperpolarization;
- nuclear magnetic resonance;
- spin–lattice relaxation
How to live longer: A fully deuterated 13C methoxy group (13CD3O) is presented as a new long-lived hyperpolarization unit for designing a sensitive 13C magnetic resonance probe. By utilizing the unit, a hyperpolarized magnetic resonance probe for sensing hypochlorous acid was successfully designed.