Resveratrol Still Has Something To Say about Aging!

Authors

  • Prof. Dr. Stéphane Quideau,

    Corresponding author
    1. Univ. Bordeaux, Institut des Sciences Moléculaires (CNRS-UMR 5255) & Institut Européen de Chimie et Biologie, 2 rue Robert Escarpit, 33607 Pessac Cedex (France)
    • Univ. Bordeaux, Institut des Sciences Moléculaires (CNRS-UMR 5255) & Institut Européen de Chimie et Biologie, 2 rue Robert Escarpit, 33607 Pessac Cedex (France)
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  • Dr. Denis Deffieux,

    1. Univ. Bordeaux, Institut des Sciences Moléculaires (CNRS-UMR 5255) & Institut Européen de Chimie et Biologie, 2 rue Robert Escarpit, 33607 Pessac Cedex (France)
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  • Dr. Laurent Pouységu

    1. Univ. Bordeaux, Institut des Sciences Moléculaires (CNRS-UMR 5255) & Institut Européen de Chimie et Biologie, 2 rue Robert Escarpit, 33607 Pessac Cedex (France)
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Abstract

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A votre Santé! The mechanism by which resveratrol, a hydroxystilbenoid polyphenol found in grapes and present in wine, exerts antiaging metabolic benefits has been uncovered. Chung and co-workers have found that it works by inhibiting cAMP phosphodiesterases, thus triggering a signaling cascade that leads to the possible activation of the mammalian enzyme sirtuin 1.

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