Across bonds: The first successful iridium-catalyzed asymmetric hydroalkynylation of nonpolar alkenes with good to excellent enantioselectivity is described (see scheme; cod=1,5-cyclooctadiene, DCE=1,2-dichloroethane). This catalytic system exhibits good functional group compatibility as NH2, OH, Br, F, and SiMe3 groups remain intact during the reaction.
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