Enantioselective Oxidation of Aldehydes Catalyzed by Alcohol Dehydrogenase

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Errata

This article is corrected by:

  1. Errata: Corrigendum: Enantioselective Oxidation of Aldehydes Catalyzed by Alcohol Dehydrogenase Volume 51, Issue 48, 11924, Article first published online: 21 November 2012

  • Support by the Deutsche Bundesstiftung Umwelt, ChemBioTec (AZ 13253) is gratefully acknowledged.

Abstract

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Teaching old dogs new tricks: Alcohol dehydrogenases (ADHs) may be established redox biocatalysts but they still are good for a few surprises. ADHs can be used to oxidize aldehydes, and this was demonstrated by the oxidative dynamic kinetic resolution of profens. In the presence of a suitable cofactor regeneration system, this reaction can occur with high selectivity.

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