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Keywords:

  • C[BOND]H functionalization;
  • dehydrogenative Heck reaction;
  • heterocycles;
  • rhodium;
  • salicylaldehydes
Thumbnail image of graphical abstract

Your CHOice! An efficient RhIII-catalyzed dehydrogenative Heck reaction (DHR) of salicylaldehydes with different classes of olefins extends the oxidative Heck reaction to aldehyde C[BOND]H bonds. Several structural motifs similar to natural products and bioactive molecules such as aurones, flavones, 2′-hydroxychalcones, and flavanones could be efficiently produced. Initial mechanistic studies give insight into the reaction mechanism.