This study was supported by the MEXT (priority area 477 Japan), the Core-to-Core Program of the JSPS, and the DFG (grant number DO 729/4). We thank Kenji Sakota (Kyushu University) and Shun-ichi Ishiuchi (Tokyo Institute of Technology) for stimulating discussions. M. Schmies is grateful for an Elsa Neumann fellowship.
Watching Water Migration around a Peptide Bond†
Article first published online: 15 JUN 2012
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 51, Issue 27, pages 6604–6607, July 2, 2012
How to Cite
Tanabe, K., Miyazaki, M., Schmies, M., Patzer, A., Schütz, M., Sekiya, H., Sakai, M., Dopfer, O. and Fujii, M. (2012), Watching Water Migration around a Peptide Bond. Angew. Chem. Int. Ed., 51: 6604–6607. doi: 10.1002/anie.201203296
- Issue published online: 27 JUN 2012
- Article first published online: 15 JUN 2012
- Manuscript Received: 29 APR 2012
- DFG. Grant Number: DO 729/4
- hydrogen bonds;
- IR spectroscopy;
A long and winding road: The motion of a single water ligand around a peptide bond in acetanilide was probed in real time by time-resolved IR spectroscopy. Triggered by photoionization, the H2O ligand is released from the CO site of the peptide linkage and trapped after a migration time of 5 ps at the NH site of the same peptide bond (see picture).