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Gold Vinylidene Complexes: Intermolecular C(sp3)[BOND]H Insertions and Cyclopropanations Pathways


  • We thank Umicore AG & Co. KG for the generous donation of gold salts.


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Highly reactive gold vinylidene species are used for intermolecular C(sp3)[BOND]H insertions into unactivated alkanes (see scheme). In addition, they can be regarded as synthons for alkylidene carbenes. Initiated by cyclopropanation of the vinylidene species/alkylidene carbenoide, cyclobutene derivatives are formed in a diastereoselective fashion by a ring-enlargement cascade in only one step.

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