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Keywords:

  • C[BOND]H activation;
  • Heck reaction;
  • olefination;
  • rhodium;
  • triazenes
Thumbnail image of graphical abstract

C[BOND]H activation/functionalization is one of the most effective ways to assemble complex organic scaffolds. A vital limitation is the need for a directing group that remains in the product architecture and restricts structural diversity. In their Communication on page 7242 ff., Y. Huang et al. describe a triazine directing group for Cmath image[BOND]H activation/functionalization. This group exhibits substantial post-functionalization synthetic versatility, thus allowing for a range of further transformations.