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Essay
Challenges for Academic Drug Discovery
Article first published online: 24 OCT 2012
DOI: 10.1002/anie.201204625
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Issue
Angewandte Chemie International Edition
Volume 51, Issue 47, pages 11680–11684, November 19, 2012
Additional Information
How to Cite
Jorgensen, W. L. (2012), Challenges for Academic Drug Discovery. Angew. Chem. Int. Ed., 51: 11680–11684. doi: 10.1002/anie.201204625
Publication History
- Issue published online: 14 NOV 2012
- Article first published online: 24 OCT 2012
- Manuscript Received: 13 JUN 2012
- Abstract
- Article
- References
- Cited By
Keywords:
- drug discovery;
- high-throughput screening;
- lead optimization;
- pharmacology;
- virtual screening
Modus operandi: There is increased interest and activity in drug discovery at universities and other non-profit organizations. The essay addresses challenges associated with progress in this area. Lead optimization and preclinical testing are identified as key bottlenecks.