Rhodium-Catalyzed Three-Component Cross-Addition of Silylacetylenes, Alkynyl Esters, and Electron-Deficient Alkenes or Isocyanates


  • This work was supported partly by Grants-in-Aid for Scientific Research (Nos. 23105512, 20675002, and 21⋅906) from the MEXT (Japan). We thank Umicore for generous support in supplying rhodium complexes.


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‘Rh'oad crossing: A cationic RhI/(cod)2 complex catalyzes the chemo-, regio-, and stereoselective title reaction with electron-deficient alkenes leading to substituted 1,3-dienes. The analogous three-component cross-addition involving isocyanates instead of alkenes has also been developed.