Get access

Rhodium-Catalyzed Three-Component Cross-Addition of Silylacetylenes, Alkynyl Esters, and Electron-Deficient Alkenes or Isocyanates


  • This work was supported partly by Grants-in-Aid for Scientific Research (Nos. 23105512, 20675002, and 21⋅906) from the MEXT (Japan). We thank Umicore for generous support in supplying rhodium complexes.


original image

‘Rh'oad crossing: A cationic RhI/(cod)2 complex catalyzes the chemo-, regio-, and stereoselective title reaction with electron-deficient alkenes leading to substituted 1,3-dienes. The analogous three-component cross-addition involving isocyanates instead of alkenes has also been developed.

Get access to the full text of this article