Supported by NIH grants R01 GM055237 (M.E.) and R01 GM071461 (E.R.). We thank Dr. Markus Voehler and Dr. Min-Kyu Cho for help with NMR acquisition, Raquel Rozner and Ryan Merrihue for assistance with UV melting experiments, and Prof. Nicholas Reiter for helpful discussions.
2′-Fluoro RNA Shows Increased Watson–Crick H-Bonding Strength and Stacking Relative to RNA: Evidence from NMR and Thermodynamic Data†
Article first published online: 10 OCT 2012
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 51, Issue 47, pages 11863–11866, November 19, 2012
How to Cite
Patra, A., Paolillo, M., Charisse, K., Manoharan, M., Rozners, E. and Egli, M. (2012), 2′-Fluoro RNA Shows Increased Watson–Crick H-Bonding Strength and Stacking Relative to RNA: Evidence from NMR and Thermodynamic Data . Angew. Chem. Int. Ed., 51: 11863–11866. doi: 10.1002/anie.201204946
- Issue published online: 14 NOV 2012
- Article first published online: 10 OCT 2012
- Manuscript Revised: 21 AUG 2012
- Manuscript Received: 25 JUN 2012
- NIH. Grant Numbers: R01 GM055237, R01 GM071461
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