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Keywords:

  • aldehyde synthesis;
  • ester reduction;
  • homogeneous catalysis;
  • hydrosilylation;
  • iridium catalysis
Thumbnail image of graphical abstract

Trumping DIBALH: A new method for reduction of esters to aldehydes through silyl acetal intermediates involves a single-step hydrosilylation catalyzed by a readily available iridium complex, [{Ir(coe)2Cl}2] (see scheme; coe=cyclooctene). The low catalyst loading, mild reaction conditions, high conversions, and broad substrate scope make this method a superior alternative to ester reduction using DIBALH.