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99TcO4: Selective Recognition and Trapping in Aqueous Solution


  • This work was financially supported by the Italian Ministry of Research (MIUR), project Supramolecular Devices. (PRIN 2008HZJW2L_003).


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Too hot to handle: Unprecedented affinity and specificity for 99TcO4 in aqueous solution was shown with the p-xylyl azacryptand in the hexaprotonated form (see scheme). A crystal structure of the complex reveals how the anion fits within the cavity of the cage, and the formation of multiple H-bond interactions with protonated amino groups stabilize the adduct.